Cyp17a1蛋白
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Cyp17a1蛋白
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http://www.delta-f.com/highchemical/protac%20linker?page=7550 WebApr 9, 2024 · 本研究主要探讨新疆阿魏中的化学物质、抗癌的作用机制及可能作用的靶点,通过网络药理学研究帮助筛选新疆阿魏的药效物质基础,对进一步研究其抗肿瘤作用单体成分及作用靶点提供理论基础。. 1方法. 1.1新疆阿魏有效成分及靶点的筛选. 利用草药-中医证候 ...
WebJan 22, 2012 · Cytochrome P450 17A1 (also known as CYP17A1 and cytochrome P450c17) catalyses the biosynthesis of androgens in humans. As prostate cancer cells proliferate … Web肾上腺皮质腺瘤CYP17A1及3BHSD2蛋白的免疫组化研究. 目的:应用免疫组织化学染色方法观察17α羟化酶 (CYP17A1),3β羟基类固醇脱氢酶2 (3BHSD2)在人正常肾上腺及其肿瘤组织中的分布特点,探讨CYP17A1,3BHSD2免疫组化检测对病理诊断肾上腺醛固酮分泌腺瘤 (APA),皮质醇分泌腺瘤 ...
Web反馈墙 ( 0) 通用注释. 亚单元: N/A. 功能: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. WebCYP17A1. Cytochrome P450 17A1 ( steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. [5] It is ubiquitously expressed in many tissues and cell types, including the zona reticularis and zona ...
Web使用 cyp17a1 (e6y3s) 兔单克隆抗体 对人肾上腺皮质的提取物进行蛋白印迹分析。 对小鼠睾丸提取物 CYP17A1 进行免疫沉淀。 泳道 1 为 10% 输入,泳道 2 为兔 (DA1E) 单克隆抗体 IgG XP ® 同型对照 #3900,泳道 3 …
WebSep 26, 2024 · cyp17a1是雄激素产生过程中最重要的酶,而阿比特龙是针对此酶的抑制剂。 当CYP17A1酶被抑制以后,雄激素的产生将受阻。 恩杂鲁胺则是靶向作用于雄激素受体(AndrogenReceptor,AR)上的LBD结构域,使雄激素不能与AR结合,阻断AR信号通路。 orchid grove vero beach flWebCYP21A2蛋白;细胞色素P450家族成员21B (CYP21A2)重组蛋白两个建议:. 1、用非变性纯化样品去做EK酶切、纯化。. 如果融合蛋白的降解是从N端开始的,而C端没有降解,那么应该能够拿到38肽。. 我曾经有个这么个类似情况,酶切后证实是N端降解,C端的目的蛋白好 … iqap online alcorWeb说明书. CYP17A1 抗体 D-12 是小鼠单克隆 IgG 2a κ, CYP17A1抗体, 在 12篇文献中引用 ,规格为 200 µg/ml. 免疫原氨基酸序列461-508位于human物种的CYP17A1的C … iqarus afghanistan limitedWeb进一步实验证实CPSF6是通过APA调节作用于下游靶点基因人宫颈癌癌基因2(HCCR2),使其具有缩短3'UTR的转录本高表达,翻译更多的蛋白,进而调节肝癌的增殖和转移过程。另外,实验中发现let-7a、let-7c、miR-26a三种miRNA结合在CPSF6基因3'UTR上直接抑制基因的 … orchid grow mix fine gradeWebJan 22, 2012 · Cytochrome P450 17A1 (also known as CYP17A1 and cytochrome P450c17) catalyses the biosynthesis of androgens in humans. As prostate cancer cells proliferate in response to androgen steroids, CYP17A1 inhibition is a new strategy to prevent androgen synthesis and treat lethal metastatic castration-resistant prostate cancer, but drug … orchid grove in florida cityhttp://kns55.zh.eastview.com/kcms/detail/detailall.aspx?filename=1021623197.nh&dbcode=CMFD&dbname=CMFDTEMP orchid grow light reviewsWebCYP17A1 ( シトクロム P450 17A1, steroid 17-alpha-monooxygenase 17α-hydroxylase/17,20 lyase/17,20 desmolase) はヒトにおいて CYP17A1 遺伝子がコードす … orchid grower science fair projects