USD $ 336.00 – USD $ 987.00. MagReSyn® HILIC magnetic beads provides a highly reproducible and fully automatable solution for parallel protein sample clean-up prior to MS analysis. The product is compatible with a range of common contaminants which interfere in the generation of high-quality data from MS analysis of samples. WebTen milligrams (10 mg) of ZIC®-HILIC beads (10 μM, 100 Å, from SeQuant AB, Umea, Sweden) were applied to enrich glycopeptide from tryptic resulting samples from standard glycoprotein, protein mixture and HeLa cell . S4 membrane protein. Tryptic peptides were reconstituted in Solution A (0.5% TFA and 80% ACN), and then
An integrated sample pretreatment platform for quantitative N ...
WebMar 26, 2014 · The C 18 RP-PGC SPE column was made by packing 10 mg of C 18 beads on the top of a 10-mg well-packed PGC column. More adsorbents (at a ratio of 60:1 with protein) were packed for complex samples. Preparation of HILIC-SPE tips. HILIC-SPE tips were prepared as previously described . Briefly, the GELoader tip was first packed with a … WebMar 22, 2024 · The modified SP3 approach is used in quantitative in-depth proteome analyses to compare it with commercial paramagnetic bead-based HILIC methods … cumberland tyler tx
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WebMay 29, 2024 · This is because, in order for glycopeptides to be captured by HILIC beads, a minimum degree of local hydrophilicity is needed, which does not appear to be provided by the paucimannosidic N-glycopepitdes. 54 This indicates that the nature of the individual glycan significantly influences the HILIC retention behavior of these lowly hydrophilic ... WebTo expand the knowledge of serum N-glycan profiles in important mammalian model systems, in this study, we combined MALDI-TOF-MS analysis and HILIC-UPLC profiling of released N-glycans together with glycosidase treatments to characterize the glycan structures present in rhesus macaque serum. WebMar 10, 2024 · Four sample preparation methods, including the filter-aided sample preparation (FASP), two single-pot solid-phase-enhanced sample preparations (SP3) on carboxylated or HILIC paramagnetic beads,... cumberland \u0026 erly